Failure of antibiotic treatment in microbial populations
نویسندگان
چکیده
منابع مشابه
Failure of antibiotic treatment in microbial populations.
The tolerance of bacterial populations to biocidal or antibiotic treatment has been well documented in both biofilm and planktonic settings. However, there is still very little known about the mechanisms that produce this tolerance. Evidence that small, non-mutant subpopulations of bacteria are not affected by an antibiotic challenge has been accumulating and provides an attractive explanation ...
متن کاملEarly antibiotic treatment failure.
There is no consensus on the definition of treatment failure. It is usually based on clinical signs, although microbiological and other biological markers may prove of value in the future. The major risk factors associated with treatment failure include an inadequate antimicrobial spectrum of the prescribed antibiotic and lack of, or insufficient, control of the source of the infection. In cert...
متن کاملAntibiotic treatment in vitro of phenotypically tolerant bacterial populations.
OBJECTIVES Most pharmacodynamic models used for design of treatment regimens are based on time-kill data obtained with normal cells in the susceptible state without taking into account the killing kinetics of the antibiotic-tolerant cells in the population. We compared the microbiological efficacy of six antibiotics against tolerant cells and by mathematical modelling explored the potential cli...
متن کاملsurvey microbial decomposition leaf litter of salix sp. populus sp. robinia sp. in artificial stream
مطالعه اکولوژیک از سرچشمه رودخانه قره سو(سراب روانسر) در استان کرمانشاه واقع در غرب ایران در پائیز 1378 انجام شد، حداکثر دمای آب 20 درجه سانتی گراد بود، هنگام مطالعه دما در سرچشمه 18 سانتی گراد بود، مقدار عناصر شیمیایی آب اندازه گیری نشد. در این پژوهش لاشبرگ های درختی از بید، چنار، اقاقیا جمع آوری سپس توسط بخش هرباریوم دانشکده کشاورزی دانشگاه شناسایی شدند. وزن خاکستر خشک afdm در(نمونه برداری ...
15 صفحه اولAntibiotic Treatment Affects Intestinal Permeability and Gut Microbial Composition in Wistar Rats Dependent on Antibiotic Class
Antibiotics are frequently administered orally to treat bacterial infections not necessarily related to the gastrointestinal system. This has adverse effects on the commensal gut microbial community, as it disrupts the intricate balance between specific bacterial groups within this ecosystem, potentially leading to dysbiosis. We hypothesized that modulation of community composition and function...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Mathematical Biology
سال: 2008
ISSN: 0303-6812,1432-1416
DOI: 10.1007/s00285-008-0243-6